Synthesis of highly deuterated amino acids.
نویسندگان
چکیده
منابع مشابه
Synthesis of highly deuterated amino acids.
Since the discovery of deuterium,' there has been considerable interest in the preparation of a variety of compounds in which hydrogen has been replaced by this heavier isotope. Some of the research has centered around the synthesis of deuterated compounds for biological study.2 While not occupying a place of prominence in this work, the preparation of deuterated amino acids has been studied in...
متن کاملHelix propensity of highly fluorinated amino acids.
Highly fluorinated amino acids have been used to stabilize helical proteins for potential application in various protein-based biotechnologies. To gain further insight into the effect of these highly fluorinated amino acids on helix formation exclusively, we measured the helix propensity of three highly fluorinated amino acids: (S)-5,5,5,5',5',5'-hexafluoroleucine (Hfl), (S)-2-amino-4,4,4-trifl...
متن کاملSynthesis of Amino Acids in the Rumen.
Science, a weekly journal founded in 1880, is published each Friday by the American Association for the Advancement of Science at the Business Press, 10 McGovern Ave., Lancaster, Pa. Editorial and Advertising Offices, 1515 Massachusetts Ave., N.\., Washington 5, D. C. Telephone, Executive 6060. Cable address, SCIMAG, Washington, D. C. Entered as second-class matter at the Post Office at Lancast...
متن کاملSynthesis of cationic porphyrin modified amino acids.
Derivatives of amino acids bearing a porphyrin moiety on a side chain were synthesized by coupling a porphyrin to a glutamic acid side chain; the utility of these compounds was demonstrated by their use in solid-phase synthesis of a peptide bearing a cationic porphyrin and by studying its DNA-binding properties.
متن کاملStereoselective synthesis of b-amino acids
Due to their potential biomedicinal and synthetic applications, b-amino acids have attracted a great deal of attention recently [1–6]. The derived b-peptides of several amino acids have been reported to exhibit certain secondary structures and special stability against peptidase [7,8]. For example, the b-oligopeptides of six b-amino acid residues form stable helices in methanol [8]. Furthermore...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1966
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.55.3.453